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Publications
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  1. Cabrera-Pardo, J.R.; Chai, D.I.; Liu, S.; Mrksich, M.; Kozmin, S.A. Label-Assisted Mass Spectrometry for the Acceleration of Reaction Discovery and Optimization. Nature Chemistry 2013, 5, pp 423-427. Nature Chemistry
  2. Cui, J.; Chai, D.I.; Miller, C.; Hao, J.; Thomas, C.; Wang, J.Q.; Scheidt, K.A.; Kozmin, S.A. Assembly of Four Diverse Heterocyclic Libraries Enabled by Prins Cyclization, Au-Catalyzed Enyne Cycloisomerization, and Automated Amide Synthesis. J. Org. Chem. 2012, 77, pp 7435-7470. Journal of Organic Chemistry
  3. Türkmen, Y.E.; Montavon, T.J.; Kozmin, S.A.; Rawal, V.H. Silver-Catalyzed Formal Inverse Electron-Demand Diels-Alder Reaction of 1,2-Diazines and Siloxy Alkynes. J. Am. Chem. Soc. 2012, 134, pp 9062-9065. Journal of the American Chemical Society
  4. Brady, P.B.; Yamamoto, H., Rapid and Stereochemically Flexible Synthesis of Polyprionates: Super-Silyl-Governed Aldol Cascades, Angew. Chem., Int. Ed. 2012, 51, pp 1942-1946 Angewandte Chemie, International Edition
  5. Kuznetsov, A; Gevorgyan, V., General and Practical One-Pot Synthesis of Dihydrobenzosiloles from Styrenes, Org. Lett. 2012, 14, pp 914-917 Organic Letters
  6. Zhu, Y.; Rawal, V.H., Palladium-Catalyzed C3-Benzylation of Indoles, J. Am. Chem. Soc. 2012, 134, pp 111-114 Journal of the American Chemical Society
  7. Montavon, T. J.; Li, J.; Cabrera-Pardo, J.R.; Mrksich, M.; Kozmin, S.A., Three-component reaction discovery enabled by mass spectrometry of self-assembled monolayers, Nature Chemistry. 2012, 4, pp 45-51 Nature Chemistry
  8. Gurard-Levin, Z. A.; Scholle, M. D.; Eisenberg, A. H.; Mrksich, M., High Throughput Screening of Small Molecule Libraries using SAMDI Mass Spectrometry, ACS Comb. Sci. 2011, 13, pp 347-350 ACS Combinatorial Science
  9. Li, Z.; Gevorgyan, V., One-Pot Arylative Epoxidation of Ketones by Employing Amphoteric Bromoperfluoroarenes, Angew. Chem., Int. Ed. 2011, 51, pp 1225-1227 Angewandte Chemie International Edition
  10. Saadi, J; Akakura, M.; Yamamoto, H.J., Rapid, One-Pot Synthesis of β-Siloxy-α-haloaldehydes, J. Am. Chem. Soc. 2011, 133, pp 14248–14251 Journal of the American Chemical Society
  11. Wang, J.; Crane, E.A.; Scheidt, K., Highly Stereoselective Brønsted Acid Catalyzed Synthesis of Spirooxindole Pyrans, Org. Lett. 2011, 13, pp 3086-3089 Organic Letters
  12. Cui, J.; Hao, J.; Ulanovskaya, O. A.; Dundas, J.; Liang, J.; Kozmin, S. A., Creation and manipulation of common functional groups en route to a skeletally diverse chemical library, PNAS. 2011, 108, pp 6763-676 Proceedings of the National Academy of Sciences of the United States of America
  13. Adamian, L.; Naveed, H.; Liang, J., Lipid-binding surfaces of membrane proteins: Evidence from evolutionary and structural analysis, Biochimica et Biophysica Acta (BBA) - Biomembranes. 2011, 1808, pp 1092-1102 Biochimica et Biophysica Acta (BBA) - Biomembranes
  14. Dundas, J.; Adamian, L.; Liang, J., Structural Signatures of Enzyme Binding Pockets from Order-Independent Surface Alignment: A Study of Metalloendopeptidase and NAD Binding Proteins, Journal of Molecular Biology. 2011, 406, pp 713-729 Journal of Molecular Biology
  15. Albert, B. J.; Yamaoka, Y.; Yamamoto, H., Rapid Total Syntheses Utilizing “Supersilyl” Chemistry, Angew. Chem., Int. Ed.. 2011, 50, pp 2610-2612 Angewandte Chemie International Edition
  16. Ulanovskaya, O. A.; Cui, J.; Kron, S. J.; Kozmin, S. A., A Pairwise Chemical Genetic Screen Identifies New Inhibitors of Glucose Transport, Chemistry & Biology. 2011, 18, pp 222-230 Chemistry & Biology
  17. Crane, E.; Scheidt, K. A., Prins-Type Macrocyclizations as an Efficient Ring Closing Strategy in Natural Product Synthesis, Angew. Chem., Int. Ed. 2010, 49, pp 8316-8326 Angewandte Chemie International Edition
  18. Chernyak, D.; Skontos, C.; Gevorgyan, V., Two-Component Approach Toward a Fully Substituted N-Fused Pyrrole Ring, Organic Letters. 2010, 12, pp 3242-3245 Organic Letters
  19. Albert, B. J.; Yamamoto, H., A Triple-Aldol Cascade Reaction for the Rapid Assembly of Polyketides, Angew. Chem., Int. Ed. 2010, 49, pp 2747-2749 Angewandte Chemie International Edition
  20. Cheon, C.H.; Imahori, T.; Yamamoto, H., Development of a new Lewis base-tolerant chiral LBA and its application to catalytic asymmetric protonation reaction, Chem. Commun. (Camb.). 2010, 7, 6980-6982 Chemical Communications
  21. Cheon, C.H.; Yamamoto, H., N-Triflylthiophosphoramide Catalyzed Enantioselective Mukaiyama Aldol Reaction of Aldehydes with Silyl Enol Ethers of Ketones, Org. Lett.. 2010, 12, 2476-2479 Organic Letters
  22. Chernyak, D.; Chernyak, N.; Gevorgyan, V., General and Efficient Cu-Catalyzed Three Component Coupling Reaction Toward Imidazoheterocycles: One-pot Synthesis of Alpidem and Zolpidem, Angew. Chem., Int. Ed. 2010, 49, 2743-2746 Angewandte Chemie International Edition
  23. Chernyak, D.; Chernyak, N.; Gevorgyan, V., Efficient and General Synthesis of 3-Aminoindolines and 3-Aminoindoles via Copper-Catalyzed Three-Component Coupling Reaction, Adv. Synth. Cat. 2010, 352, 961-966 Advanced Synthesis and Catalysis
  24. Liang, J.; Qian, H., Computational cellular dynamics based on the chemical master equation: A challange for understanding complexity, Journal of Computer Science and Technology. 2010, 25, 154-168 Journal of Computer Science and Technology
  25. Yousuke, Y.; Yamamoto, H., Super Silyl Stereo-Directing Groups for Complete 1,5-Syn and -Anti Stereoselectivities in the Aldol Reactions of β-Siloxy Methyl Ketones with Aldehydes, J. Am. Chem. Soc. 2010, 132, 5354–5356. Journal of the American Chemical Society
  26. Zhu, Y.; Malerich, J. P.; Rawal, V. H., Squaramide-Catalyzed Enantioselective Michael Addition of Diphenyl Phosphite to Nitroalkenes, Angew. Chem., Int. Ed. 2010, 49, 153-156. Angewandte Chemie International Edition
  27. Cui, J.; Matsumoto, K.; Wang, C. Y.; Peter, M. E.; Kozmin S. A., Synthesis of a High-Purity Chemical Library Reveals a Potent Inducer of Oxidative Stress, ChemBioChem. 2010, 1224-1227. ChemBioChem
  28. Lee, H.; Suzuki, M.; Cui, J.; Kozmin, S. A. Synthesis of an Azide-Tagged Library of 2,3-Dihydro-4-quinolones, J. Org. Chem. 2010, 75, 1756-1759. The Journal of Organic Chemistry
  29. Sun, J.; Keller, V. A.; Meyer, S. T.; Kozmin, S. A., Silver-Catalyzed Aldehyde Olefination Using Siloxyalkynes, Adv. Synth. Catal. 2010, 352, 839-842. Advanced Synthesis and Catalysis
  30. Gondi, V. B.; Hagihara, K.; Rawal, V. H., Diastereoselective and enantioselective synthesis of tertiary α-hydroxyphosphonates via hydrogen bond catalysis, Angew. Chem., Int. Ed. 2009, 47, 776-779. Angewandte Chemie International Edition
  31. Lu, H.; Liang, J., Perturbation-based Markovian Transmission Model for Probing Allosteric Dynamics of Large Macromolecular Assembling: A Study of GroEL-GroES, PLoS Comput. Biol. 2009, 5. PLoS Computational Biology